5-Amino-1MQ
10mg
5-Amino-1MQ 10mg
Research Compound Lyophilized Powder
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5-Amino-1MQ

Selective NNMT Inhibitor

$60.00
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What It Is

A small-molecule selective inhibitor of NNMT, an enzyme that consumes methyl groups from S-adenosyl-methionine (SAM) and depletes the NAD+ precursor nicotinamide. Investigated as a research tool for studying methyl-donor balance and adipocyte metabolism in preclinical models.

How It Works

1
5-Amino-1MQ enters the research model
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2
Binds and inhibits the NNMT enzyme
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3
SAM and nicotinamide pools are preserved
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4
Cellular methylation capacity and NAD+ salvage are studied

What Researchers Study It For

Adipocyte energy expenditure models
NAD+ salvage pathway investigations
Methyl-donor and SAM/SAH ratio studies
Diet-induced obesity preclinical research

Common Research Protocols

In published preclinical literature, 5-Amino-1MQ has been administered orally or via intraperitoneal injection in rodent models, with dosing typically scaled by body weight in mg/kg ranges.

Community Interest Areas

The metabolic-research community has shown sustained interest in 5-Amino-1MQ because NNMT inhibition sits at the intersection of two highly studied pathways — methyl-donor metabolism and NAD+ biology. Investigators have explored its activity in adipose-tissue models, muscle-cell energetics, and nutrient-sensing networks, often in parallel with other NAD+-pathway research compounds.

Selective NNMT inhibitor with preclinical research literature
Peer-Reviewed Published studies across methyl-donor and NAD+ biology

For research purposes only. Not intended for consumption, clinical application, or diagnostic use.

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